Charlotte Fowler was born in Cohocton, New York, August 14, 1814. She was the fourth in a family of eight children. Her father, Horace Fowler, was a deacon and judge. Her mother, Martha Howe, was an intellectual, who died when Wells was five years old, but her teachings left a lasting impression upon the daughter. Wells received most of her education in the district school, with only two winters of three months each of instruction in the Franklin Academy in Prattsburgh, New York, beginning in autumn 1831. She was otherwise self-taught, with a wide range of reading. Her older brothers, Orson and Lorenzo, were among the first to examine and believe the doctrines of Franz Joseph Gall and Johann Spurzheim. The increasing interest in the science of phrenology was greatly the result of the brothers' lifelong work.
Career
Wells studied and became interested in Spurzheim's works, teaching the first class in phrenology in the United States, and thereafter, her life was devoted to promoting it. Urged by her brothers, she closed her school in 1837, and joined them in New York City in the family-run business of O.S. & L.N. Fowler, a lecture bureau, museum, and publishing house, where she served as proofreader, writer, business manager, and editor. She also maintained the organization's cabinet and was also instrumental in keeping the permanent offices from being abandoned. When Orson was in the field lecturing, and Lorenzo was establishing a branch in London, England, she had charge of the business in New York, and was considered instrumental in its success. Samuel Roberts Wells was studying to be a doctor when he attended a course of lectures delivered by the Fowler brothers in Boston. He was impressed with the theme and resolved to investigate it, his first ideas of phrenology having been obtained as a boy from a chart which had been marked by Charlotte Fowler, then in her teens. In 1843, he joined the Fowler brothers's institute, and in the following year, he formed a co-partnership with the Fowler brothers, at their Nassau Street, New York office, the name having been changed to Fowler & Wells. Wells organized the book business and gave a new impetus to the Phrenological Journal. On October 13, 1844, Charlotte and Samuel were married. The Wells worked together for 31 years. For long periods of time, she was left with the control of the entire business, while her husband and brothers were traveling through countries, spreading the science and items for their cabinet. After Lorenzo moved to England in 1855, the firm's ownership passed to the Wells. After the husband's death in 1875, she became the sole proprietor and manager for nine years. In 1884, she formed a stock company, Fowler & Wells Company, of which she was president, and published the American Phrenological Journal. She also served as vice-president and one of the instructors of the American Institute of Phrenology. In addition, in 1863, she was one of the founders, and served as a trustee of the New York Medical College for Women.