Prince Charles Thomas was the first-born son from the marriage of Prince Dominic Constantine, Prince of Löwenstein-Wertheim-Rochefort with Maria Leopoldine, Princess of Hohenlohe-Bartenstein. Prince Charles had six sisters and three half siblings from his father's second marriage. He and his younger brotherConstantine were raised during the final years of the Holy Roman Empire. They were very aware of the privileges of the class of Imperial Princes. They were educated at court in Würzburg and later at the court of Prince Clemens Wenceslaus of Saxony, the Prince-Elector of Trier. Nothing is known about any higher education that Charles Thomas may have enjoyed. In 1802, he participated in a diplomatic mission of the Löwenstein-Wertheim-Rosenberg family to Paris. His father's territory was mediatized during the events following the French Revolution. The Löwenstein territories were divided between the newly elevated Grand Duchies of Baden and Hesse and the Kingdoms of Bavaria and Württemberg. Charles Thomas joined the Austrian army and fought in several battles of the Napoleonic Wars. Most recently, he served as major in the Galician Ulanes Regiment "Prince of Schwarzenberg" No. 2. In 1812 and 1813, the family lost its territory on the left bank of the Rhine, including Rochefort. This led to a name change: the House of Löwenstein-Wertheim-Rochefort changed its name to Löwenstein-Wertheim-Rosenberg. In 1814, Charles Thomas's father died. He resigned from the military and took up administration of the family possessions. As a member of the high nobility, he held a seat in the First Chamber in Baden, Bavaria, Hesse and Württemberg. However, he had little interest in the political issues of those four states. Initially, his senior officials concerned themselves with the interests of the high nobility. From the early 1830s, his son Constatine did the same. After Constantine died in 1838, the senior officials took over again. Throughout his life, Charles Thomas felt a strong bond with the Austrian Empire and its ruling Habsburg dynasty. He married an Austrian wife and took up permanent residence in Vienna in the 1840s. As he grew older, he devoted more and more time to his Catholic faith and developed a devotion, which served as a model for his grandson and successor Charles Henry.