The section south of Sheppard was once interrupted at Highway 401. The construction of the highway lead to the break since the late 1940s and fully by 1956. An $11 million overpass and partial interchange of the freeway was built and opened on October 18, 1987 over the objections of many area residents on concerns over increased traffic volume. In an attempt to address these concerns, it was initially restricted to transit buses and emergency vehicles. After a few months of widely reported public pressure, Scarborough City Council voted February 18, 1988 to open the overpass to general traffic. A partial interchange is provided between Brimley Road and Highway 401, with westbound access to Highway 401 from northbound Brimley Road, and southbound access to Brimley Road from eastbound Highway 401. Eastbound traffic may also access northbound Brimley Road via the Progress Avenue exit.
Public transit
The main Toronto Transit Commissionbus route on Brimley Road is the 21 Brimley, which runs from Steeles Avenue to Eglinton Avenue, stopping on the way through the Scarborough Centre RT station. At Eglinton, it turns west to the Kennedysubway station. The old route of 128 Brimley North, which originally ran from Scarborough Centre to Steeles through McCowan Road and Sheppard Avenue, had started when the RT opened in 1985 and merged with the 21 in 1999. Prior to 1985, TTC service on Brimley north of Sheppard was served by a branch of the 57 Midland route. The 903 Kennedy–Scarborough Centre Express runs on Brimley between Scarborough Centre and Eglinton during peak hours, stopping only at Lawrence Avenue. The 12A/B Kingston Road also serves Brimley from Kingston Road to Eglinton. South of Kingston Road, Brimley Road South has served as the off-street loop for a number of routes since the 1950s, with the 12 Kingston Road doing this since 1968. In 2002, the TTC examined the feasibility of building a Scarborough RT station at Brimley Road. It concluded that demands are not enough, and instead a pedestrian walkway was built towards Scarborough Centre station. In 2007, it was stated that the issue will be re-examined when significant land developments take place west of Brimley Road near the proposed location of Brimley station. In February 2008 the TTC made a motion that the current study should include the addition of a station where the existing line crosses Brimley Road. From September 1989 to September 1993Brimley Rd North of Steeles was served by 128A Brimley North from Scarborough Centre to 14th Avenue by the TTC. In September 1993 for about a year Markham Transit took over operations on Brimley Rd between Steeles Ave and 14th Ave as Route 6 Brimley while TTC operated south of Steeles Ave to Scarborough Centre. To this day there is no bus service on Brimley Rd North of Steeles Ave due to low ridership.
Resthaven Memorial Gardens; west side between St Clair and Kingston Road.
St Andrew's Cemetery, east of Brimley on St Andrew's Road.
Ebenezer United Church, northwest corner of Steeles and Brimley in Markham built 1876 replacing earlier one at southeast corner on Thomas Harding farm in Scarborough c. 1852