N'Dong had previously planned to enter the NCAA with an American college in hopes to gain major exposure. However, due to his weight being under what American colleges were looking for at the time, those plans were ultimately aborted. Instead, as a 21 year old, N'Dong had to look into an alternative plan for increasing his talents due to Senegal's professional leagues performing less-than-par of expectations for him. During that time, Dallas Mavericks agent Amadou Fall recommended that he trained in Dirk Nowitzki's former club and improve his skills there. Sometime in early 1999, N'Dong signed with the SpVgg Rattelsdorf in Germany for one-and-a-half seasons of play there. After being undrafted in 1999, he continued training for the next three years in the TSV Tröster Breitengüßbach to further improve his game. In 2003, he would finally improve his skills to play in the Basketball Bundesligaprofessional league with the TSK uniVersa Bamberg. After playing a season there, he would sign a two-year deal with the Dijon Basket out in the LNB Pro A. During this time, he would gain further exposure from NBA scouts. The 2005–06 NBA season would be the first and only NBA season for the 28-year-old 7 ft 0 in center to play in the National Basketball Association with the Los Angeles Clippers. During this season, N'Dong barely played any notable parts with the team, appearing in 23 games with a 7-minute per game average, starting only once for them. However, the Clippers would ultimately have a surprising season under their belt in his sole season there, making it to the Western Conference semifinals for the first time in franchise history, barely upsetting the Phoenix Suns in the process. In December 2006, he signed with the Russian club Spartak St. Petersburg. N'Dong moved to the Spanish ACB league later that season and signed with Unicaja Málaga for the 2006–07 ACB League Play-Offs to replace the injured Daniel Santiago. On July 14, 2007, he re-signed with Malaga on a one-season contract. He has also played with the Cleveland CavaliersNBA Summer League squad in 2007. In 2009, he signed a two-year contract worth €3.2 million net income with the Spanish league club FC Barcelona. In 2011, he signed a one-year extension contract with Regal Barcelona. In the summer of 2012, he signed a one-year contract with Galatasaray Medical Park. On June 16, 2013, the day after Galatasaray won the 2012–13 league championship, he announced that he was going to retire.
