In the year 2011, a sophisticated Los Angeles Company, Nanolabs, prepares to advertise a cancer cure in the form of nano-engines, microscopic molecular machines which mutate and restore organic tissue cell by cell. Genius Buck Hogan starts to have serious doubts when lab animals start to die. Profit-greedy CEO Donald ignores him and devises human tests and news conferences. The same night, a strange-looking masked figure traps and anesthetizes Hogan. When hogan awakens, he learns one of his kidneys has been expertly replaced with a biodegradable sac that according to later publications, holds corrosive acid. The masked man promises Hogan an antidote only if he complies in picking up and delivering three packages. When the departmental LAPD refuses to help, and Hogan's fiancee Angeline is abducted, Hogan rips open a package and discovers it is empty. Hogan realizes that the courier act was a ruse to cause him to touch boxes coated with nano-engines, which penetrate his skin and are reacting with the sac. Hogan traces the potential culprit, fellow employee and career rival Malcolm Garvey, who forces the couple into Nanolabs at gunpoint during Donald's big press tour. Revealing that the cancer cure is actually a carcinogen, Garvey also tells that the nano-engines inside Hogan have converted his implant into a destructive bomb. In the following panic, Garvey is shot dead and Angeline and Hogan remain in the building. Fortunately, Angeline happens to be a surgeon and executes an effective bomb-ectomy on the spot. They flee as the lab explodes, but Garvey's caution is lost in the pointless electronic media.
Critical reception to the film has been negative. TV Guide wrote Some praise went to the plot of the film "that the nano-engines... assemble an explosive device inside Hogan's gut is a neat payoff; too bad Wynne couldn't think of a better way to get there ". However, criticism was directed to the running of the film: "The game is mostly up at the 70-minute mark,... director Paul Wynne pads the remaining running time with a protracted car chase and... fruitless attacks on shallow TV journalism." Surprise praise was given to cinematographer Angel Colmenares... BOMBSHELL is worth watching, if only for Angel Colmenares' snazzy cinematography, which paints the future-shock sets with electric colors and sometimes slips into time-lapse imagery."