In the mid-1970s, Bob Schreck began working for Creation Entertainment organizing and running conventions around the country, where he got to know most of the era’s comic book professionals, and met aspirants and up-and-comers such as Matt Wagner, who has called Schreck "a major force in the comics industry." In the early 1980s he worked in marketing at Marvel Comics. In 1985 Schreck and his future wife Diana Schutz were hired as, respectively, administrative director and editor of. Under their stewardship Comico rose to the third best-selling comics publisher, after Marvel and DC. After a brief stint at Graphitti Designs, Schreck worked at Dark Horse Comics from 1990-97, where he served as marketing director, editor and group editor. During this time Dark Horse became the third best-selling comics publisher in the country. As editor, Schreck brought several talents to a wider audience, including Mike Allred and Paul Pope, who credits Schreck as an important factor in his career, and was the editor of, among other titles, Frank Miller's Sin City, The Big Guy and Rusty the Boy Robot, Madman, Art Adams’s Monkeyman and O'Brien, and the anthology title Dark Horse Presents. Schreck was later instrumental in compelling Frank Miller to work with director Robert Rodriguez on a film version of Sin City. He left Dark Horse in 1997 and shortly thereafter co-founded Oni Press with Joe Nozemack. Oni's goal was publishing comics and graphic novels the founders would want to read. Unsatisfied with the material that was dominating the industry, they believed firmly that sequential art could be used to tell virtually any story. Oni titles Schreck edited include Kevin Smith's Clerks and Jay and Silent Bob comics, Whiteout, Bad Boy by Frank Miller and Simon Bisley, and the award-winning Oni Double Feature. After having been courted by DC Comics for over a decade, Schreck left Oni to join them as editor of the Batman titles, which included the acclaimed storyline ', and the mini-series The Dark Knight Strikes Again, and ' as well as recruitment of writers Judd Winick, David Lapham, and Brad Meltzer with his first work in comics. Schreck was also the editor of the Green Lantern books, Green Arrow including the acclaimed Quiver series by frequent Schreck collaborator Kevin Smith, All-Star Superman by Grant Morrison and Frank Quirely, and All-Star Batman by Frank Miller and Jim Lee. For DC's Vertigo imprint he produced the award-winning Daytripper, Sweet Tooth, and the horror anthology Toe Tags, which featured a story by film director George Romero After leaving DC in January 2009, Schreck joined IDW Publishing as a senior editor, where he also wrote the comic book seriesJurassic Park: Redemption. In 2010, he was named editor-in-chief of Legendary Comics, a division he co-founded with editor Greg Tumbarello, where they launched as a top ten publisher with their inaugural title Holy Terror by Frank Miller. Other works they published include the Eisner Award-nominated Annihilator by Grant Morrison and Frazer Irving, The Tower Chronicles by Matt Wagner and Simon Bisley, A Town Called Dragon by Judd Winick and Geoff Shaw, Shadow Walk by Mark Waid and Shane Davis, and Cops for Criminals by Steven Grant and Pete Woods, as well as NY Times #1 Best Selling Graphic NovelPacific Rim: Tales from Year Zero, NY Times Best Seller Godzilla: Awakening, and tie-ins to Warcraft, andKing Kong. After retiring from Legendary, Schreck became Deputy Director of the Comic Book Legal Defense Fund in 2019. Schreck credits his editorial philosophy in part to the influence of Archie Goodwin, explaining: "I try to provide very fertile topsoil. A place for these people to take root and grow... a certain amount of stepping back and compassion, just being able to listen to what it is... many times the writer or the artist you’re working with, they’re not quite sure what it is they want to say at this juncture. So you’re there to hear things that even they’re not picking up on and help them see it."