The son of Senior Constable William Renfrey, and Mary Jane Renfrey, née Percy, Ethelbert Luxmore Renfrey was born in South Australia on 5 May 1879. He married Ethel Maud Percy on 23 September 1921. They had two children: Mary Lois, and Ronald.
Renfrey, a two time Stawell Gift runner-up, then played with West Broken Hill and was a member of their 1901 and 1903 Broken Hill Football League premiership winning teams.
Renfrey joined West Perth and participated in their 1905 premiership side. The following year, West Perth made another grand final, but Renfrey missed the game through injury.
In 1907 he competed in his fourth state, playing 15 games for St Kilda. His last game was St Kilda's historic semi final against Carlton, their first ever final.
Having captained Sturt in his first season, Renfrey was made captain-coach in 1910 and remained in that position for the rest of his time at the club. Renfrey represented South Australia in a total of 11 interstate matches and captained the 1911 Adelaide Carnival team. The South Australians finished the carnival unbeaten, defeating the VFL representative side by 43 points. In the 1913 finals series, Sturt were upset by West Adelaide and following the game several players accused Renfrey of "playing dead". With five members of the team refusing to play with him again, Renfrey was sacked by the committee. He was reinstated the next evening after a vote of confidence was carried and took part in their next game, a loss to his former club North Adelaide. Following the match he was involved in a fight with prominent Sturt player Albert Heinrichs and never played for the club again. Despite the bitter end to his time with Sturt, he was later named on the interchange bench in their official "Team of the Century".
Coaching
He joined South Adelaide as non playing coach in 1914 and the following year guided them to third position on the ladder. The league went into recess during the war and when it returned in 1919, Renfrey coached for one final season.
Military service
He enlisted in the First AIF on 4 January 1916, and was discharged on 31 August 1916.
After football
He became a bookmaker.
Death
He died from a self inflicted gunshot wound in the South Parklands of Adelaide on 29 April 1940.