Humphreys was born in Claiborne County in the Territory of Mississippi, on the Bayou Pierre. He was educated in New Jersey and enrolled at West Point in the same class as Robert E. Lee and Joseph E. Johnston. However, he was expelled in 1826 when he participated in a "Christmas frolic" that ended up turning into the Eggnog Riot. Upon his return to Mississippi, he was elected to the state senate representing his native county, serving from 1839 to 1844. In 1846, he moved to Sunflower County, Mississippi, and founded Itta Bena. He developed a cotton plantation there.
Humphreys raised a company and was commissioned a Captain in the Confederate States Army in 1861. Being part of the 21st Mississippi Infantry Regiment he was elected to the rank of Colonel the same year. Brigaded with other regiments under command of Brig. Gen. William Barksdale he fought in the Eastern Theater. At the Battle of Gettysburg in 1863 Humphreys's regiment was part of the force that attacked Federal positions at the Peach Orchard, driving the defenders back toward Cemetery Ridge. Humphreys took command of the brigade after the death of Barksdale. He was subsequently promoted to Brigadier General, and remained in command of the brigade through the end of the war.
Political career
After the surrender of the Confederate Army, Southern politicians and Army officers were not automatically pardoned and were forbidden to hold public office. At the time of his candidacy, Benjamin Humphreys was unpardoned, and President Andrew Johnson did not want him elected. Unwilling to withdraw his candidacy, on October 2, 1865, Humphreys was elected as a Democrat, but was not immediately recognized as the Governor of Mississippi. Without presidential approval, on October 16, 1865, Humphreys had himself inaugurated and sworn in as the 26th Governor of Mississippi. By October 26, 1865, Mississippi provisional Governor, William L. Sharkey, received from PresidentAndrew Johnson a pardon authorizing political office under the Reconstruction plan. He won re-election in 1868 and continued with a second term, but with the beginning of Congressional control of Reconstruction he was physically removed by occupying U.S. armed forces on June 15 of that year. As a Democratic Governor of the State of Mississippi, he encouraged Jim Crow laws. In his own words: After his retirement from politics, Humphreys entered a career in insurance in Jackson, Mississippi. He continued there until his retirement in 1877, when he moved to his plantation in Leflore County, Mississippi, where he died in 1882. He is buried in Wintergreen Cemetery, Port Gibson, Mississippi. Humphreys County, Mississippi, is named after him. His son, also named Benjamin G. Humphreys, entered into a political career of his own. He became a Congressman and was on the Harbors and Rivers Committee, where he was instrumental in the successful amendment that created and added levees to the charter of the commission.