Athel Cornish-Bowden


Athel Cornish-Bowden is a biochemist known for his numerous textbooks, particularly those on enzyme kinetics and his work on metabolic control analysis.

Education and career

Athel Cornish-Bowden worked on pepsin catalysis.. This began a life long pursuit of work on enzyme catalysis and in later years work on the control of metabolism. More recently he has also turned his attention to work related to the origin and nature of life. He worked with Daniel E. Koshland Jr. and Jeremy R. Knowles.

Research

Cornish-Bowden has authored over 200 peer-reviewed papers and nine textbooks on topics related to enzyme kinetics, mathematics and historical perspectives in science.
Cornish-Bowden's research can be divided into three primary areas: Enzyme kinetics, metabolic control and the origin of life. The following lists some of the topics and selected references to the work carried out and published by Cornish-Bowden:
Mechanisms of Pepsin Catalysis
Binding of ligands to Proteins
Kinetics of nitrite reductase
Kinetics of nitrate reductase
The evolution of macromolecules
Properties of multienzyme systems
The theory of self-organizing systems
His current interests include the definition of life and the capacity for life to self-organize.
Cornish-Bowden is most well known for his introduction of the direct-linear plot for estimating enzyme parameters, his work on Hexokinase evolution and kinetics, and his insight into the control and regulation of metabolism

Selected publications

*