Arylsulfatase A
Arylsulfatase A is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into cerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene.Pathology
A deficiency is associated with metachromatic leukodystrophy, an autosomal recessive disease.Biochemistry
Arylsulfatase A is inhibited by phosphate, which forms a covalent bond with the active site 3-oxoalanine.
