Having moved to Myrtle, Mississippi before high school, the 5'9" Herrington became a star player at Myrtle High School and received numerous honors, including being named to the Clarion-Ledger's Dandy Dozen as a senior. Herrington averaged 31.0 points, 22.0 rebounds, 6.0 assists and 5.0 steals as a senior and helped lead Myrtle High to the 2003 Class 1A state title and to Class 1A state runner-up finishes as a sophomore and junior. Herrington, who also excelled in track, helped lead Myrtle High to the 2001, 2002 and 2003 Class 1A state championship in track and was a 15-time state champion in track as she won the 100-meter high hurdles, long jump, 200 meters, 4x100-meter relay and 4x200-meter relay her sophomore, junior and senior years. Because of her religion which stated females must wear feminine apparel, her mother encouraged her to wear a skirt throughout her high school basketball career.
College career
While attending the University of Mississippi in Oxford, Mississippi, Herrington became one of the most decorated athletes of all time playing for coach Carol Ross's Ole Miss Rebels women's basketball team from 2003 to 2007. During her senior year, she averaged a team leading 18.1 points per game, which ranked second in the SEC and 32nd in the NCAA. She also led the team with 146 assists and 118 steals. Her 3.8 steals per game was first in the NCAA and SEC, while she ranked fourth in assists in the SEC with 4.8 per game Herrington is just the fifth player in NCAA history to record over 2,000 points, 1,000 rebounds, 300 assists and 300 steals joining Cheryl Miller, Chamique Holdsclaw, Tamika Catchings and Sophia Young. Price was named 2007 SEC Defensive Player of the Year, becoming the first player in the history of the league to win the award two times. She was a unanimous selection to the 2007 All-SEC First Team by the league coaches.
The day after her 22nd birthday, Herrington was chosen with the third overall pick by the Chicago Sky, an expansion team of the WNBA. Herrington became the first Ole Miss player selected in the first round of the draft's eleven-year history. She is also just the second Lady Rebel to be selected in the draft. On September 8, 2007 Herrington was named 2007 WNBA Rookie of the Year. She played for Mallorca in Spain during the 2008–09 WNBA off-season. Price was traded to the Atlanta Dream on August 12, 2009 in exchange for Tamera Young. In 2014, she joined the Los Angeles Sparks. On February 10, 2015, Herrington signed with the Washington Mystics.
Personal life
Price married Reginald Herrington on October 11, 2009.