Alanine—tRNA ligase
In enzymology, an alanine-tRNA ligase is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, L-alanine, and tRNA, whereas its 3 products are AMP, diphosphate, and L-alanyl-tRNA.
This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-alanine:tRNAAla ligase . Other names in common use include alanyl-tRNA synthetase, alanyl-transfer ribonucleate synthetase, alanyl-transfer RNA synthetase, alanyl-transfer ribonucleic acid synthetase, alanine-transfer RNA ligase, alanine transfer RNA synthetase, alanine tRNA synthetase, alanine translase, alanyl-transfer ribonucleate synthase, AlaRS, and Ala-tRNA synthetase. This enzyme participates in alanine and aspartate metabolism and aminoacyl-trna biosynthesis.As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes,,,,,, and.
