Akuammicine
Akuammicine is an alkaloid found in Vinca minor and Aspidosperma. It is a μ-opioid receptor agonist while also agonizing the κ and δ-opioid receptors. Agonistic activity at both human variants of the σ-sigma receptors has been indicated but is not yet proven, so have possible mechanisms of action at the NMDA receptor and glycine receptor.
