77-LH-28-1

77-LH-28-1 is a selective agonist of muscarinic acetylcholine receptor subtype 1 discovered in 2008. It is an allosteric agonist, exhibiting over 100-fold specificity for M₁ over other muscarinic receptor subtypes. 77-LH-28-1 penetrates the brain by crossing the blood-brain barrier and is therefore a useful pharmacological tool with cognition enhancing effects.

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