The 45th Sustainment Brigade was originally constituted on 1 May 1936, in the Regular Army as the 45th Quartermaster Regiment. It was initially activated on 9 May 1942, at the Oakland sub-port of embarkation, California, as the 45th Quartermaster Truck Regiment. Elements of the regiment separated on 1 December 1943, and received new destinations. The Headquarters and Headquarters Detachment became HHD, 45th Quartermaster Group. The Headquarters and Headquarters Detachment, 1st, 2nd and 3rd Battalions respectively, Companies A through M were re-designated as the 346 1st through 247 2dd Quartermaster Truck Companies. The Headquarters and Headquarters Detachment, 45th Quartermaster Group, then deactivated at Camp Kilmer, New Jersey, on 26 November 1945. On 30 March 1966, the group was designated as Headquarters and Headquarters Company, 45th Support Group. Activation followed on 4 May 1966, at Fort Lee, Virginia. The group was deactivated on 15 December 1970, at Fort Lewis, Washington. On 15 September 1972 the 45th Support Group saw its latest activation at Fort Shafter, Hawaii. In August 1986, the 45th Support Group was reorganized to include command and control of the 7th Maintenance Battalion, the 124th Transportation Battalion, the 84th Engineer Battalion, the 29th Engineer Battalion and the 125th Finance Battalion. On 16 October 1993, the 45th Support Group was re-designated as the 45th Corps Support Group, the 7th Maintenance Battalion was re-designated as the 17th Corps Support Battalion, and the 124th Transportation Battalion was re-designated as the 524th Corps Support Battalion. Other subordinate units consisted of the 84th Engineer Battalion, 125th Finance Battalion, and the 29th Engineer Battalion. The 45th Corps Support Group was re-designated at the 45th Sustainment Brigade on 11 January 2006 in conjunction with the Army's Transformation Campaign Plan with assigned units of a Special Troops Battalion, the 524th Support Battalion and the 17th Support Battalion. On 7 July 2006, the 45th Sustainment Brigade deployed to Q-West, Iraq in support of Operation Iraqi Freedom. A milestone was achieved when command authority was transferred from one sustainment brigade to another in a Transfer of Authority ceremony on 29 August 2006. This marked the first of such a transfer in the history of the United States Army. The Brigade was relieved of its duties by the 3rd Sustainment Brigade on 26 June 2007. On January 2009, the 45th Sustainment Brigade deployed to Afghanistan in support of Operation Enduring Freedom. In January 2012, the 45th Sustainment Brigade deployed once again to Afghanistan in support of Operation Enduring Freedom. On June 30, 2015, the 45th Sustainment Brigade was redesignated as the 25th Sustainment Brigade, 25th Infantry Division. Last BDE commander of the 45th Sustainment Brigade was COL Gregory G. Boyd.
