The Spartans finished the 2000–01 season 28–5, 13–3 in Big Ten playt to finish in second place. Michigan State received a No. 1 seed in the NCAA Tournament, their fourth straight trip to the Tournament, and advanced the Final Four, their third straight trip under Tom Izzo. The Spartans lost Charlie Bell to graduation and freshman Zach Randolph and sophomore Jason Richardson to the NBA Draft following the season.
Season summary
After three consecutive years of trips to the Final Four, the Spartans began the season ranked No. 15 in the AP Poll. Michigan State was led by sophomore Marcus Taylor, freshman Chris Hill, and junior Adam Ballinger. The Spartans participated in the Preseason NIT where they defeated Detroit Mercy and No. 24 Oklahoma at Breslin Center, but then fell to No. 18 Syracuse and No. 23 Fresno State at Madison Square Garden. The Spartans also suffered non-conference losses to No. 6 Florida and No. 16 Stanford, but did beat No. 6 Arizona in a rematch of their Final Four clash the previous Spring. MSU finished the non-conference season at 9–4 and ranked No. 19 in the country. In Big Ten play, MSU started the season with three straight losses, the last to Wisconsin, which snapped MSU's 53-game home winning streak. The Spartans did defeat No. 12 Illinois, No. 18 Ohio Stateat home and on the road, and No. 23 Indiana. Michigan State finished the conference schedule at 10–6 and in fourth place with an overall record of 19–10. The Spartans slipped out of the ranking following their opening conference losses and remained unranked the remainder of the season. MSU lost in the quarterfinals of the Big Ten Tournament to No. 23 Indiana marking the first time since 1997 that Michigan State did not win either the Big Ten regular season or tournament title. The Spartans received an at-large bid as a No. 10 seed in the NCAA Tournament, their fifth consecutive trip. The Spartans were eliminated in the First Round by NC State. Following the season, sophomore Marcus Taylor declared for the NBA Draft.
Roster
Schedule and results
!colspan=9 style=| Exhibition !colspan=9 style=| Non-conference regular season !colspan=9 style=|Big Ten regular season !colspan=9 style=|Big Ten Tournament !colspan=9 style=|NCAA Tournament