March 5 – Pleading illness Giolitti resigns over the issue of national railways.
March 12 – An interim government under Tommaso Tittoni takes over.
March 28 – On the recommendation of Giolitti, Alessandro Fortis forms a new government, he is the first Jewish Prime Minister of Italy. The government undertakes the nationalization of the railways, after confronting a railroad strike in April that could have paralyzed transportation in the country. Railroad workers became public employees, which deprives them of the right to strike.
April 22 – The strike of railway workers ends with an agreement over arbitration between the government and railroad men. The Ferrovie dello Stato is instituted, taking control over the majority of the national railways, which were private until then, with a total of of lines.
June
June 11 – Pope Pius X promulgates the encyclical Il fermo proposito, which establishes Azione Cattolica as a non-political lay organization under the direct control of bishops. It was established after an earlier similar organization, Opera dei Congressi was disbanded in 1904 because many of its members were siding with modernism. Catholics were allowed by the Pope to vote "to help the maintenance of the social order".
July
July 1 – The three principal railway companies in Italy are brought together with a number of private operators into the nationalised Ferrovie dello Stato.
September
September 8 – An earthquake strikes southern Italy with a magnitude of 7.2, damaging parts of Lipari Island and Messina Province, and killing between 557 and 2,500 people. The earthquake particularly affects the Calabria region, destroying as many as 25 villages, and 14,000 homes. Fortis visited the area and introduced a special law to aid these southern regions. This measure was the first real acknowledgment by the Italian state of the fundamental problems underlying southern underdevelopment.
December
December 3 – Foreign Minister Tittoni resigns over his proposal to reduce the duty on Spanish wine in connection with an Italo-Spanish commercial treaty that created turmoil among the rural classes.
December 17 – The government of Prime Minister Fortis resigns the proposal to reduce the duty on Spanish wine in connection with an Italo-Spanish commercial treaty.
December 23 – Fortis forms a new government, without Tittoni.