15-hydroxyicosatetraenoate dehydrogenase


In enzymology, a 15-hydroxyicosatetraenoate dehydrogenase is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are 15-Hydroxyicosatetraenoic acid, NAD+, and NADP+, whereas its 4 products are 15-oxo-5,8,11-cis-13-trans-icosatetraenoate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is -15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD+ 15-oxidoreductase. This enzyme is also called 15-hydroxyeicosatetraenoate dehydrogenase. This enzyme participates in arachidonic acid metabolism.